Description

Hexafluoroisopropyl Trifluoromethanesulfonate is a highly reactive and versatile fluorinated sulfonate ester. This compound serves as a powerful alkylating and trifluoromethanesulfonylating agent, prized for its ability to introduce the hexafluoroisopropyl group into complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for synthesis and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorination improves efficacy and environmental profile.
• Polymer & Material Science: Acts as a monomer or modifier in the creation of specialty fluoropolymers with unique thermal, chemical, and surface properties.
• Ligand & Catalyst Preparation: Employed in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis and cross-coupling reactions.
• Electrolyte Additive: Investigated for use in high-performance lithium-ion battery electrolytes to improve stability and conductivity.
• Organic Synthesis Reagent: A superior reagent for Friedel-Crafts alkylations, esterifications, and other reactions requiring a strong electrophile.

Basic Information

Product Name	Hexafluoroisopropyl Trifluoromethanesulfonate
CAS No.	156241-41-7
Molecular Formula	C5H3F9O3S
Molecular Weight	314.13 g/mol
Synonyms	1,1,1,3,3,3-Hexafluoro-2-propyl trifluoromethanesulfonate; Hexafluoroisopropyl Triflate; (CF3)2CHO3SCF3; HFP-OTf; Trifluoromethanesulfonic Acid 1,1,1,3,3,3-Hexafluoro-2-Propyl Ester; 2-(Trifluoromethanesulfonyloxy)-1,1,1,3,3,3-hexafluoropropane
EINECS	Contact for details

Quality Control

Our Hexafluoroisopropyl Trifluoromethanesulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). Our QC procedures include advanced analytical techniques to verify identity, potency, and impurity profiles, meeting the stringent requirements of our global customer base in research and regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%
Density (at 20°C)	~1.65 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.