Description

1,3-Dihydro-5-Nitro-3-Spirocyclohexaneindol-2-One is a specialized spirocyclic indole derivative, a high-value intermediate in advanced organic synthesis. Its unique molecular architecture, featuring a nitro-substituted indole fused to a cyclohexane ring, makes it a critical building block for constructing complex pharmacophores. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, or insecticides with novel modes of action.
• Material Science: Potential building block for advanced organic electronic materials or specialty polymers due to its conjugated indole system.
• Chemical Synthesis: Used in academic and industrial R&D for methodological studies in spirocyclization and nitro-group transformations.
• Biochemical Probe Development: May be utilized to create molecular probes for studying biological pathways and enzyme interactions.

Basic Information

Product Name	1,3-Dihydro-5-Nitro-3-Spirocyclohexaneindol-2-One
CAS No.	156232-54-1
Molecular Formula	C14H16N2O3
Molecular Weight	260.29 g/mol
Synonyms	5-Nitro-3-spirocyclohexane-1,3-dihydro-2H-indol-2-one; 3-Spirocyclohexane-5-nitroindolin-2-one; 5-Nitrospiro[cyclohexane-1,3'-indolin]-2'-one; 2H-Indol-2-one, 1,3-dihydro-5-nitro-3-spirocyclohexane-; Spiro[cyclohexane-1,3'-indole]-2'(1'H)-one, 5'-nitro-; 156232-54-1; 5-Nitro-3-spirocyclohexyloxindole
EINECS	Contact for details

Quality Control

Our 1,3-Dihydro-5-Nitro-3-Spirocyclohexaneindol-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.