Description

5-Chloro-1H-Spiro[Indole-3,4'-Oxane]-2-One is a high-value, synthetically versatile spirocyclic indole derivative. This compound serves as a critical pharmaceutical intermediate and a sophisticated chemical building block for advanced organic synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used as a core scaffold for developing new-generation herbicides and fungicides with novel modes of action.
• Organic Synthesis Building Block: Employed in constructing complex spirocyclic and heterocyclic frameworks for material science and medicinal chemistry applications.
• Biochemical Research: Acts as a specialized reagent or ligand in the study of enzyme inhibition and receptor binding assays.
• Fine Chemical Production: Serves as a starting material for the manufacture of high-purity specialty chemicals used in advanced manufacturing processes.

Basic Information

Product Name	5-Chloro-1H-Spiro[Indole-3,4'-Oxane]-2-One
CAS No.	156232-36-9
Molecular Formula	C12H10ClNO2
Molecular Weight	235.67 g/mol
Synonyms	5-Chloro-1H-spiro[indole-3,4'-oxane]-2-one; 5-Chloro-1H-spiro[indole-3,4'-oxan]-2-one; 5-Chloro-1H-spiro[indoline-3,4'-oxane]-2-one; 5-Chloro-1H-spiro[indole-3,4'-tetrahydropyran]-2-one; 5-Chloro-2-oxo-1H-spiro[indole-3,4'-oxane]; 156232-36-9; Spiro[indole-3,4'-oxane]-2-one, 5-chloro-1H-
EINECS	Contact for details

Quality Control

Our 5-Chloro-1H-Spiro[Indole-3,4'-Oxane]-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.