Description

Spirocyclohexane-1,2-1,3Dioxino4,5,6-Hiindolizin-8-Ol, Octahydro-9-(Methoxymethoxy)-8-Methyl-, 3As-(3A.Alpha.,8.Beta.,9.Beta.,9A.Beta.,9B.Alpha.)- is a complex, high-purity spirocyclic organic compound with the CAS number 156206-07-4. This molecule is valued for its intricate, rigid three-dimensional structure, making it a critical chiral intermediate in advanced synthetic chemistry. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) or anti-infective therapies.
• Asymmetric Synthesis: Utilized as a sophisticated ligand or scaffold in catalytic asymmetric reactions to induce high enantioselectivity.
• Academic & Industrial R&D: Employed in methodological research for constructing complex polycyclic and spirocyclic molecular architectures.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialty chemicals requiring specific stereochemistry.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Spirocyclohexane-1,2-1,3Dioxino4,5,6-Hiindolizin-8-Ol, Octahydro-9-(Methoxymethoxy)-8-Methyl-, 3As-(3A.Alpha.,8.Beta.,9.Beta.,9A.Beta.,9B.Alpha.)-
CAS No.	156206-07-4
Molecular Formula	C₁₇H₂₇NO₅
Molecular Weight	325.40 g/mol
Synonyms	Octahydro-9-(methoxymethoxy)-8-methyl-spiro[cyclohexane-1,2'-[1,3]dioxino[4,5,6-hi]indolizin]-8'-ol (3aR,8S,9S,9aR,9bS)-isomer; (3aR,8S,9S,9aR,9bS)-Octahydro-9-(methoxymethoxy)-8-methyl-spiro[cyclohexane-1,2'-[1,3]dioxino[4,5,6-hi]indolizin]-8'-ol; Spiro[cyclohexane-1,2'-[1,3]dioxino[4,5,6-hi]indolizin]-8'-ol, octahydro-9-(methoxymethoxy)-8-methyl-, (3aR,8S,9S,9aR,9bS)-; CAS 156206-07-4; 156206-07-4; Advanced Spirocyclic Intermediate; Chiral Spirocyclic Alcohol Derivative.
EINECS	Contact for details

Quality Control

Our Spirocyclohexane-1,2-1,3Dioxino4,5,6-Hiindolizin-8-Ol derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific GMP or research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.