Description

(4-Iodo-Benzoyl)-Phosphonic Acid Diethyl Ester is a high-value organophosphorus building block featuring a reactive iodoarene moiety. This compound is essential for facilitating advanced cross-coupling reactions and serving as a versatile synthon in complex organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators that require specific aryl-iodide functionalities.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized phosphonate-based ligands for metal catalysis.
• Material Science: Building block for creating functionalized polymers and organic electronic materials with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for biochemical research.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific, multi-step synthetic routes.

Basic Information

Product Name	(4-Iodo-Benzoyl)-Phosphonic Acid Diethyl Ester
CAS No.	156017-40-2
Molecular Formula	C11H14IO4P
Molecular Weight	368.11 g/mol
Synonyms	Diethyl (4-Iodobenzoyl)phosphonate; (4-Iodobenzoyl)phosphonic Acid Diethyl Ester; Diethyl P-(4-Iodobenzoyl)phosphonate; Phosphonic Acid, P-(4-Iodobenzoyl)-, Diethyl Ester; 4-Iodobenzoylphosphonic Acid Diethyl Ester; Diethyl 4-Iodobenzoylphosphonate
EINECS	Contact for details

Quality Control

Every batch of (4-Iodo-Benzoyl)-Phosphonic Acid Diethyl Ester is produced and tested under strict quality management protocols to ensure consistency and reliability for critical R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to support applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.