Description

3-(Bromomethyl)Benzoic Acid n-Succinimid is a high-purity chemical intermediate featuring a reactive bromomethyl group and an activated ester (N-succinimidyl) moiety. This bifunctional structure is critical for its primary role as a versatile linker in the synthesis of complex molecules, enabling efficient conjugation under mild conditions. It is an essential building block for researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for antibody-drug conjugates (ADCs) and targeted therapeutics.
• Bioconjugation Reagent: Used to covalently link drugs, dyes, or other functional molecules to proteins, peptides, or antibodies via its reactive N-hydroxysuccinimide (NHS) ester group.
• Peptide Synthesis: Employed in solid-phase and solution-phase peptide chemistry to introduce specific functional handles or for side-chain modification.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the creation of functional polymers, hydrogels, and smart materials.
• Chemical Biology Probes: Utilized in the development of activity-based probes and diagnostic agents for research and assay development.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and herbicides.

Basic Information

Item	Details
Product Name	3-(Bromomethyl)Benzoic Acid n-Succinimid
CAS No.	155863-35-7
Molecular Formula	C12H10BrNO4
Molecular Weight	312.12 g/mol
Synonyms	3-(Bromomethyl)benzoic acid N-succinimidyl ester; 3-(Bromomethyl)benzoic acid N-hydroxysuccinimide ester; 3-(Bromomethyl)benzoyloxysuccinimide; 3-(Bromomethyl)benzoic acid NHS ester; N-Succinimidyl 3-(bromomethyl)benzoate; N-Hydroxysuccinimide ester of 3-(bromomethyl)benzoic acid; 3-Bromomethylbenzoyl NHS ester
EINECS	Contact for details

Quality Control

Every batch of 3-(Bromomethyl)Benzoic Acid n-Succinimid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent in-house specifications, which are designed to meet the high-purity demands of research and pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions, preferably with desiccant, to prevent hydrolysis and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.