Description

2,2-Dimethyl-1,3-Dioxane-5-Carboxylic Acid Methyl Ester is a specialized acetal-protected ester derivative, serving as a crucial chiral building block and synthetic intermediate in advanced organic synthesis. Its value lies in providing a masked carboxylic acid functionality that is stable under a wide range of reaction conditions, enabling complex multi-step syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to construct molecules with defined three-dimensional structures.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and advanced materials.
• Academic & Industrial Research: A valuable reagent for methodological development and exploring new synthetic pathways in R&D laboratories.
• Peptide Mimetics: Useful in the synthesis of peptide analogs and other bio-active compounds where acid-sensitive protecting groups are required.

Basic Information

Product Name	2,2-Dimethyl-1,3-Dioxane-5-Carboxylic Acid Methyl Ester
CAS No.	155818-14-7
Molecular Formula	C8H14O5
Molecular Weight	190.19 g/mol
Synonyms	Methyl 2,2-Dimethyl-1,3-dioxane-5-carboxylate; (R)-(-)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic Acid Methyl Ester (related isomer); 5-Carbomethoxy-2,2-dimethyl-1,3-dioxane; Acetonide-protected glyceric acid methyl ester; Glyceric acid acetonide methyl ester; Dioxane carboxylic acid ester; Chiral dioxane derivative
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-1,3-Dioxane-5-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.