Description

1H-Pyrazolo[3,4-B]Pyridine-3-Carbonitrile,6-Fluoro-(9Ci) is a high-purity fluorinated pyrazolopyridine derivative, a crucial nitrogen-containing heterocyclic building block. Its value lies in its role as a sophisticated intermediate for synthesizing advanced pharmaceutical compounds and agrochemicals, enabling the introduction of specific functional groups. This product is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that require specific fluorinated heterocyclic cores for enhanced activity and selectivity.
• Material Science Research: Serves as a precursor for developing organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-3-Carbonitrile,6-Fluoro-(9Ci)
CAS No.	155601-83-5
Molecular Formula	C7H3FN4
Molecular Weight	162.12 g/mol
Synonyms	6-Fluoro-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile; 6-Fluoropyrazolo[3,4-b]pyridine-3-carbonitrile; 6-Fluoro-3-cyanopyrazolo[3,4-b]pyridine; 6-Fluoro-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile (9CI); 155601-83-5; 6-Fluoro-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile (9CI); 6-Fluoro-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile, (9CI)
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyridine-3-Carbonitrile,6-Fluoro-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters for your regulatory and internal QA/QC requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.