Description

tert-Butyl 2-(2,6-difluoropyridin-3-yl)-2-oxoacetate is a high-value fluorinated pyridine derivative and a key synthetic intermediate in modern organic chemistry. This compound is prized for its role as a versatile building block, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the difluoropyridine moiety.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Material Science Precursor: Potential use in the development of specialty chemicals, ligands for catalysis, and advanced organic materials.

Basic Information

Product Name	tert-Butyl 2-(2,6-Difluoropyridin-3-yl)-2-oxoacetate
CAS No.	155601-70-0
Molecular Formula	C11H11F2NO3
Molecular Weight	243.21 g/mol
Synonyms	2-(2,6-Difluoropyridin-3-yl)-2-oxoacetic acid tert-butyl ester; tert-Butyl (2,6-difluoropyridin-3-yl)oxoacetate; 2-Oxo-2-(2,6-difluoro-3-pyridinyl)acetic acid 1,1-dimethylethyl ester; 155601-70-0; Oxo(2,6-difluoro-3-pyridinyl)acetic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 2-(2,6-difluoropyridin-3-yl)-2-oxoacetate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.