Description

tert-Butyl 2-Benzyl-1-Oxo-2,7-Diazaspiro[3.5]Nonane-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and diazepane scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional molecules for targeted protein degradation.
• CNS Drug Discovery: The diazaspiro[3.5]nonane core is of significant interest for developing modulators of neurological targets.
• Kinase Inhibitor Synthesis: Employed in the construction of novel kinase inhibitor candidates for oncology and inflammatory diseases.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the cGMP or non-GMP production of clinical trial materials.

Basic Information

Item	Detail
Product Name	tert-Butyl 2-Benzyl-1-Oxo-2,7-Diazaspiro[3.5]Nonane-7-Carboxylate
CAS No.	155600-89-8
Molecular Formula	C19H26N2O3
Molecular Weight	330.43 g/mol
Synonyms	7-Boc-2-benzyl-2,7-diazaspiro[3.5]nonan-1-one; tert-Butyl 2-benzyl-1-oxo-2,7-diazaspiro[3.5]nonane-7-carboxylate; 2,7-Diazaspiro[3.5]nonane-7-carboxylic acid, 2-benzyl-1-oxo-, 1,1-dimethylethyl ester; 2-Benzyl-1-oxo-2,7-diazaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester; 7-(tert-Butoxycarbonyl)-2-benzyl-2,7-diazaspiro[3.5]nonan-1-one; BOC-2-Benzyl-2,7-diazaspiro[3.5]nonan-1-one
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Benzyl-1-Oxo-2,7-Diazaspiro[3.5]Nonane-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.