Description

5-Isoxazolecarboxylic Acid, 4,5-Dihydro-3-(Hydroxymethyl)-, Methyl Ester (9Ci) is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceuticals and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to innovate and scale new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting novel therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, contributing to the development of next-generation crop protection solutions.
• Fine Chemical Production: Serves as a specialized building block for synthesizing complex molecules used in flavors, fragrances, and electronic chemicals.
• Academic & Industrial Research: Employed in chemical research for studying heterocyclic chemistry, reaction mechanisms, and developing new synthetic methodologies.
• Material Science Precursor: Potential use in the synthesis of organic ligands or functional monomers for advanced polymeric materials.

Basic Information

Product Name	5-Isoxazolecarboxylic Acid, 4,5-Dihydro-3-(Hydroxymethyl)-, Methyl Ester (9Ci)
CAS No.	155526-77-5
Molecular Formula	C7H9NO4
Molecular Weight	171.15 g/mol
Synonyms	Methyl 4,5-dihydro-3-(hydroxymethyl)isoxazole-5-carboxylate; 3-(Hydroxymethyl)-4,5-dihydroisoxazole-5-carboxylic acid methyl ester; 4,5-Dihydro-3-(hydroxymethyl)-5-isoxazolecarboxylic acid methyl ester; Dihydroisoxazole carboxylate ester; Isoxazoline derivative CAS 155526-77-5
EINECS	Contact for details

Quality Control

Our 5-Isoxazolecarboxylic Acid, 4,5-Dihydro-3-(Hydroxymethyl)-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.