Description

tert-Butyl 2-Hydroxy-5-Nitrobenzoate is a high-purity organic intermediate characterized by its nitro and phenolic ester functional groups. This compound is valued for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with nitroaromatic or salicylate-derived structures.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its nitro group for further chemical transformations.
• Organic Synthesis Building Block: Serves as a protected form of 2-hydroxy-5-nitrobenzoic acid, enabling selective reactions in multi-step synthetic routes.
• Material Science Research: Investigated for the development of specialty polymers, ligands, or functional materials due to its reactive phenolic and ester groups.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	tert-Butyl 2-Hydroxy-5-Nitrobenzoate
CAS No.	155388-63-9
Molecular Formula	C11H13NO5
Molecular Weight	239.23 g/mol
Synonyms	2-Hydroxy-5-nitrobenzoic acid tert-butyl ester; Benzoic acid, 2-hydroxy-5-nitro-, 1,1-dimethylethyl ester; tert-Butyl 5-nitro-2-hydroxybenzoate; 5-Nitrosalicylic acid tert-butyl ester; 1,1-Dimethylethyl 2-hydroxy-5-nitrobenzoate; 2-Hydroxy-5-nitro-benzoic acid tert-butyl ester; tert-Butyl 5-nitrosalicylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Hydroxy-5-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.