Description

1,4-Dioxaspiro[4.5]Decan-8-Amine:Hydrochloride is a high-purity, protected amine building block and key synthetic intermediate. Its value lies in providing a reactive amine handle that is shielded by a ketal protecting group, enabling selective chemistry in complex multi-step syntheses. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where selective functionalization of the amine is required.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug candidates, including potential central nervous system (CNS) agents and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its protected amine functionality allows for precise structural modifications.
• Organic Synthesis & Research: Serves as a versatile precursor in academic and industrial R&D for constructing spirocyclic and heterocyclic compounds.
• Peptidomimetics & Ligand Development: Employed in the design and synthesis of peptide mimics and specialized ligands for biochemical and medicinal chemistry applications.
• Fine Chemical Production: Acts as a critical intermediate in the custom synthesis of high-value, low-volume specialty chemicals for various advanced material applications.

Basic Information

Product Name	1,4-Dioxaspiro[4.5]Decan-8-Amine:Hydrochloride
CAS No.	155137-22-7
Molecular Formula	C9H18ClNO2
Molecular Weight	207.70 g/mol
Synonyms	8-Amino-1,4-dioxaspiro[4.5]decane hydrochloride; 1,4-Dioxaspiro[4.5]decan-8-amine hydrochloride; 8-Amino-1,4-dioxaspiro[4.5]decane HCl; Cyclohexanone ethylene ketal-8-amine hydrochloride; 4-Aminocyclohexanone ethylene ketal hydrochloride; Spiro[1,3-dioxolane-2,1'-cyclohexan]-4'-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.5]Decan-8-Amine:Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.