Description

Spiro[Oxirane-2,1-[1H]Pyrrolizine] (9Ci) is a specialized spirocyclic organic compound featuring a fused oxirane (epoxide) and pyrrolizine ring system, identified by CAS No. 155122-08-0. This unique molecular architecture makes it a valuable advanced synthetic intermediate and a versatile scaffold for constructing complex pharmacophores. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its three-dimensional, rigid structure.
• Organic Synthesis Reagent: Employed in the construction of complex nitrogen- and oxygen-containing heterocycles via ring-opening reactions of the epoxide moiety.
• Agrochemical Development: Investigated as a precursor for novel bioactive molecules in crop protection research.
• Academic & Industrial R&D: Utilized in chemical biology and material science research to explore new molecular properties and interactions.

Basic Information

Product Name	Spiro[Oxirane-2,1-[1H]Pyrrolizine] (9Ci)
CAS No.	155122-08-0
Molecular Formula	C8H9NO
Molecular Weight	135.16 g/mol
Synonyms	1H-Pyrrolizine, 2,3-dihydrospiro[oxirane-2,1'-[1H]pyrrolizine]; Spiro(oxirane-2,1'-pyrrolizine); 1'H-Spiro[oxirane-2,1'-pyrrolizine]; 2,3-Dihydrospiro[oxirane-2,1'(1'H)-pyrrolizine]; 155122-08-0; Spiro[oxirane-2,1'-pyrrolizine]; Spiro-oxirane-pyrrolizine
EINECS	Contact for details

Quality Control

Our Spiro[Oxirane-2,1-[1H]Pyrrolizine] (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.