Description

Ethyl 2-Chloro-2-Fluorocyclopropanecarboxylate is a high-value, multifunctional fluorinated cyclopropane building block. This compound is essential for introducing the strained, stereochemically defined cyclopropane ring into target molecules, a key structural motif in modern medicinal and agrochemical discovery. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Intermediate: Used in the research and development of next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Chemical Biology Probe Synthesis: Employed to create fluorinated and chlorinated molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Material Science Research: Serves as a precursor for developing specialty polymers and advanced materials with unique electronic or surface properties.
• Asymmetric Synthesis Building Block: Utilized in stereoselective reactions to construct complex chiral molecules due to its defined stereochemistry.
• Fluorine Chemistry Research: A valuable substrate for exploring new methodologies in organofluorine chemistry and C-F bond activation.

Basic Information

Product Name	Ethyl 2-Chloro-2-Fluorocyclopropanecarboxylate
CAS No.	155051-93-7
Molecular Formula	C6H8ClFO2
Molecular Weight	166.58 g/mol
Synonyms	2-Chloro-2-fluorocyclopropanecarboxylic acid ethyl ester; Ethyl 2-chloro-2-fluorocyclopropane-1-carboxylate; 1-Carbethoxy-2-chloro-2-fluorocyclopropane; 2-Fluoro-2-chlorocyclopropanecarboxylic acid ethyl ester; Ethyl 2-fluoro-2-chlorocyclopropanecarboxylate; 155051-93-7; 2-Chloro-2-fluorocyclopropanecarboxylic acid, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Chloro-2-Fluorocyclopropanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.