Description

Methyl 3-Iodopropiolate is a versatile iodinated alkyne ester building block, essential for advanced organic synthesis. This high-purity intermediate enables precise carbon-carbon bond formation and functional group transformations critical for pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing acetylene or iodinated moieties.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators requiring specific alkyne functionalization.
• Material Science: Serves as a monomer or cross-linking agent in the preparation of specialized polymers and advanced organic materials.
• Click Chemistry: An excellent substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create triazole linkages.
• Organic Synthesis Building Block: Facilitates Sonogashira coupling and other palladium-catalyzed cross-coupling reactions to form conjugated systems.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name	Methyl 3-Iodopropiolate
CAS No.	155004-90-3
Molecular Formula	C4H3IO2
Molecular Weight	209.97 g/mol
Synonyms	Methyl 3-Iodopropynoate; 3-Iodopropiolic Acid Methyl Ester; Methyl 3-Iodoprop-2-ynoate; Methyl 3-Iodo-2-propynoate; Propiolic acid, 3-iodo-, methyl ester; Methyl β-Iodopropiolate
EINECS	Contact for details

Quality Control

Our Methyl 3-Iodopropiolate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.