Description

2(3H)-Furanone,Dihydro-3,4-Dimethyl-5-(1-Methylethyl)-,[3S-(3Alpha,4Alpha,5Alpha)]-(9Ci) is a high-purity, stereochemically defined lactone compound of significant interest in advanced organic synthesis. This chiral building block is valued for its rigid, functionalized structure which enables the construction of complex molecular architectures with precise stereocontrol. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in projects requiring stereochemical precision.
• Asymmetric Synthesis: Serves as a versatile building block in catalytic asymmetric reactions to introduce complex, multi-substituted lactone motifs into target molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs targeting various therapeutic areas.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, flavors, fragrances, and advanced materials where specific stereochemistry is critical.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways in both university and corporate research laboratories.

Basic Information

Product Name	2(3H)-Furanone,Dihydro-3,4-Dimethyl-5-(1-Methylethyl)-,[3S-(3Alpha,4Alpha,5Alpha)]-(9Ci)
CAS No.	154968-09-9
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	(3S,4S,5S)-3,4-Dimethyl-5-(propan-2-yl)dihydrofuran-2(3H)-one; (3S,4S,5S)-3,4-Dimethyl-5-isopropyldihydrofuran-2(3H)-one; [3S-(3α,4α,5α)]-Dihydro-3,4-dimethyl-5-(1-methylethyl)-2(3H)-furanone; (3S,4S,5S)-3,4-Dimethyl-5-(1-methylethyl)-2(3H)-furanone; Stereoisomer of γ-lactone derivative
EINECS	Contact for details

Quality Control

Our production of this chiral lactone adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and mass spectrometry to confirm identity, stereochemical purity, and chemical assay. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in rigorous R&D and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.