Description

C18-Fura-2 CAS NO 154933-56-9 is a specialized, long-chain fatty acid derivative of the classic Fura-2 calcium indicator, designed for superior membrane integration and sustained intracellular signaling studies. This modified probe is critical for researchers requiring enhanced cellular retention and reduced dye leakage during long-term kinetic measurements of cytosolic calcium concentrations. It is an essential tool for advanced cell biology and pharmacology research in academic, pharmaceutical, and biotechnology sectors.

Application

• Long-term intracellular calcium imaging in cell culture and tissue models.
• Pharmacological screening for drug candidates affecting calcium-dependent pathways.
• Neuroscience research, including studies of neuronal signaling and synaptic plasticity.
• Cardiovascular research, particularly in cardiomyocyte calcium handling and contractility.
• High-content screening (HCS) and automated fluorescence microscopy platforms.
• Development of diagnostic assays for calcium-related cellular dysfunctions.

Basic Information

Item	Detail
Product Name	C18-Fura-2
CAS No.	154933-56-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fura-2 C18; Fura-2 AM C18 analog; 1-Oleoyl-2-[5-[2-[5-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]phenoxy]-2-oxazolyl]phenoxy]-sn-glycero-3-phosphocholine (possible structure-based name); Long-chain Fura-2 AM; Membrane-anchored Fura-2; C18-Fura-2 AM (if acetoxymethyl ester); Lipophilic Fura-2 derivative
EINECS	Contact for details

Quality Control

Every batch of C18-Fura-2 is produced and tested under strict quality management protocols to ensure the highest standards of purity and performance for research applications. Our quality control includes rigorous analytical testing, such as HPLC for purity and spectral analysis for functional verification. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and performance specifications is provided with each shipment to guarantee traceability and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow solid or film
Identification (HPLC/UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95%
Functional Performance (in situ)	Conforms to reference for calcium binding
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.