Description

5,8-Diazaspiro[3.5]Nonane-6,9-Dione,7-(Hydroxymethyl)-,(R)-(9Ci) is a high-purity, chiral spirocyclic compound that serves as a sophisticated building block in advanced organic synthesis. Its unique molecular architecture, featuring a spiro center and a hydroxymethyl group on the (R)-enantiomer, makes it a valuable intermediate for constructing complex, three-dimensional pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in medicinal chemistry.
• Agrochemical Synthesis: Used in the creation of novel, biologically active molecules for crop protection and pest management solutions.
• Chemical Biology Probe Development: Serves as a core scaffold for designing molecular probes to study enzyme function and biological pathways.
• Asymmetric Catalysis Ligand Precursor: Potential use in the synthesis of chiral ligands for asymmetric synthesis applications.
• Advanced Material Research: Investigated as a monomer or building block for specialty polymers with unique properties.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and the synthesis of complex natural product analogs.

Basic Information

Product Name	5,8-Diazaspiro[3.5]Nonane-6,9-Dione,7-(Hydroxymethyl)-,(R)-(9Ci)
CAS No.	154878-43-0
Molecular Formula	C8H10N2O3
Molecular Weight	182.18 g/mol
Synonyms	(R)-7-(Hydroxymethyl)-5,8-diazaspiro[3.5]nonane-6,9-dione; (7R)-7-(Hydroxymethyl)-5,8-diazaspiro[3.5]nonane-6,9-dione; 7-(Hydroxymethyl)-5,8-diazaspiro[3.5]nonane-6,9-dione, (R)-; 154878-43-0; Spirocyclic hydantoin derivative; (R)-enantiomer of hydroxymethyl-diazaspiro nonanedione
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Identity and purity are confirmed through a suite of analytical techniques including HPLC, chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.