Description

5,5-Dimethyl-3-(mesyloxymethyl)dihydro-2[3H]-furanone is a high-value, synthetically versatile heterocyclic building block. This compound is a key protected intermediate in the synthesis of complex molecules, particularly in the pharmaceutical sector. It is primarily sought after by research institutions and manufacturers engaged in developing active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial synthon in the multi-step synthesis of novel drug candidates, especially those with complex lactone or spirocyclic structures.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing chiral centers and functionalized furanone scaffolds due to its reactive mesylate leaving group.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and fungicides with specific biological activity.
• Material Science: Potential monomer or cross-linking agent in the research of specialty polymers with tailored properties.
• Academic & R&D: Employed in university and corporate laboratories for methodological studies in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	5,5-Dimethyl-3-(mesyloxymethyl)dihydro-2[3H]-furanone
CAS No.	154750-22-8
Molecular Formula	C8H14O5S
Molecular Weight	222.26 g/mol
Synonyms	3-(Methanesulfonyloxymethyl)-5,5-dimethyl-dihydro-2(3H)-furanone; 5,5-Dimethyl-3-(methylsulfonyloxymethyl)dihydrofuran-2(3H)-one; 3-(Mesyloxymethyl)-5,5-dimethyldihydrofuran-2(3H)-one; 154750-22-8; Dihydro-5,5-dimethyl-3-[(methylsulfonyl)oxy]methyl]-2(3H)-furanone
EINECS	Contact for details

Quality Control

Our production of 5,5-Dimethyl-3-(mesyloxymethyl)dihydro-2[3H]-furanone adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. We provide full traceability and comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request, supporting your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.