Description

Carbamic Acid, (3-Oxocyclobutyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic building block featuring a cyclobutanone ring fused with a carbamate protecting group. This compound matters as a key synthetic intermediate, offering a reactive ketone handle and a tert-butoxycarbonyl (Boc) protected amine precursor for constructing complex molecular architectures. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients and by fine chemical manufacturers producing advanced intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those requiring constrained cyclobutane rings.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with unique biological activity profiles.
• Peptidomimetics & PROTACs: The Boc-protected amine and ketone functionality make it valuable for constructing peptide analogs and proteolysis-targeting chimeras (PROTACs).
• Material Science Research: Acts as a monomer or precursor for developing polymers with specific thermal or mechanical properties derived from the rigid cyclobutane structure.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring advanced, multi-functional intermediates.

Basic Information

Product Name	Carbamic Acid, (3-Oxocyclobutyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	154748-49-9
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	1,1-Dimethylethyl (3-oxocyclobutyl)carbamate; tert-Butyl (3-oxocyclobutyl)carbamate; N-Boc-3-aminocyclobutanone; 3-[(tert-Butoxycarbonyl)amino]cyclobutanone; Boc-3-ACB; (3-Oxocyclobutyl)carbamic acid tert-butyl ester; N-(tert-Butoxycarbonyl)-3-aminocyclobutanone
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (3-Oxocyclobutyl)-, 1,1-Dimethylethyl Ester is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.