Description

n-Benzyloxycarbonyl D-Valine Methyl Ester is a protected amino acid derivative, specifically the methyl ester of N-Cbz-D-valine. This compound serves as a crucial chiral building block in the synthesis of complex peptides and pharmaceutical intermediates. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and protease inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate D-valine residues with orthogonal N-terminal protection.
• API Development: Serves as a building block for the research and production of Active Pharmaceutical Ingredients (APIs) requiring specific stereochemistry.
• Bioconjugation: Employed in the preparation of modified peptides for drug delivery systems and diagnostic probes.
• Chemical Biology Research: Utilized in academic and industrial R&D for studying enzyme-substrate interactions and designing enzyme inhibitors.
• Fine Chemical Synthesis: Acts as a precursor in the multi-step synthesis of complex organic molecules with high stereochemical purity.

Basic Information

Product Name	n-Benzyloxycarbonyl D-Valine Methyl Ester
CAS No.	154674-67-6
Molecular Formula	C14H19NO4
Molecular Weight	265.31 g/mol
Synonyms	N-Cbz-D-Valine Methyl Ester; N-Carbobenzoxy-D-valine Methyl Ester; Z-D-Val-OMe; (R)-2-((Benzyloxy)carbonylamino)-3-methylbutanoic Acid Methyl Ester; D-Valine, N-[(phenylmethoxy)carbonyl]-, methyl ester; Methyl N-[(benzyloxy)carbonyl]-D-valinate; Benzyloxycarbonyl-D-valine Methyl Ester; N-Benzyloxycarbonyl-D-valine Methyl Ester
EINECS	Contact for details

Quality Control

Our n-Benzyloxycarbonyl D-Valine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed HPLC, NMR, and optical rotation data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.