Description

()-2-(Trifluoromethyl)Piperidine is a high-value, fluorinated piperidine derivative, a crucial building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group on the piperidine ring, imparts significant lipophilicity and metabolic stability to target molecules, making it indispensable for modern pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of central nervous system (CNS) active drugs, protease inhibitors, and other bioactive molecules where the trifluoromethyl group enhances potency and pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials that require fluorinated components for specific thermal or chemical resistance.
• Chemical Biology & Probe Design: Utilized as a scaffold or tagging moiety in the design of molecular probes and diagnostic agents for biochemical assays.

Basic Information

Product Name	()-2-(Trifluoromethyl)Piperidine
CAS No.	154630-93-0
Molecular Formula	C6H10F3N
Molecular Weight	153.15 g/mol
Synonyms	2-(Trifluoromethyl)piperidine; α-(Trifluoromethyl)piperidine; (±)-2-(Trifluoromethyl)piperidine; rac-2-(Trifluoromethyl)piperidine; 2-Trifluoromethylpiperidine; Piperidine, 2-(trifluoromethyl)-; TL-1-149
EINECS	Contact for details

Quality Control

Our ()-2-(Trifluoromethyl)Piperidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is a fluoride/strong alkali and should be stored separately from strong acids and oxidizing agents. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.