Description

2-Sulfanyl-5H,6H,7H-Cyclopenta-[B]Pyridine-3-Carbonitrile is a specialized heterocyclic organic compound featuring a fused cyclopentapyridine core with both nitrile and sulfanyl functional groups. This unique molecular architecture makes it a versatile and high-value intermediate for advanced chemical synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating new therapeutic agents and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Synthesis: Utilized as a versatile synthon in organic chemistry for constructing complex nitrogen- and sulfur-containing heterocycles.
• Bioconjugation & Probe Development: The reactive sulfanyl and nitrile groups can be exploited for creating biochemical probes and conjugation linkers.

Basic Information

Product Name	2-Sulfanyl-5H,6H,7H-Cyclopenta-[B]Pyridine-3-Carbonitrile
CAS No.	154384-01-7
Molecular Formula	C9H8N2S
Molecular Weight	176.24 g/mol
Synonyms	2-Mercapto-5,6,7,8-tetrahydrocyclopenta[b]pyridine-3-carbonitrile; 5,6,7,8-Tetrahydrocyclopenta[b]pyridine-3-carbonitrile-2-thiol; 2-Thioxo-2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]pyridine-3-carbonitrile; Cyclopenta[b]pyridine-3-carbonitrile, 5,6,7,8-tetrahydro-2-mercapto-; 154384-01-7; 2-Sulfanyl-5,6,7,8-tetrahydrocyclopenta[b]pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 2-Sulfanyl-5H,6H,7H-Cyclopenta-[B]Pyridine-3-Carbonitrile adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and chemical identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and REACH compliance ensures a reliable and consistent supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.