Description

(S)-Methyl 2,4-Dihydroxybutanoate CAS NO 154006-52-7 is a high-value chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its bifunctional nature, featuring both hydroxyl and ester groups, makes it a versatile precursor for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of active pharmaceutical ingredients (APIs), chiral ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of various APIs, including β-blockers, antiviral agents, and other therapeutics requiring specific (S)-configuration.
• Asymmetric Synthesis: Used as a starting material or auxiliary in catalytic asymmetric reactions to introduce chiral centers into target molecules.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals where stereochemical purity is critical.
• Polymer Chemistry: Potential monomer for creating functionalized, biodegradable polyesters with tailored properties.
• Chemical Research: Valuable reagent in academic and industrial R&D for methodological development and exploring new synthetic pathways.
• Ligand and Catalyst Preparation: Building block for synthesizing chiral ligands used in homogeneous catalysis.

Basic Information

Product Name	(S)-Methyl 2,4-Dihydroxybutanoate
CAS No.	154006-52-7
Molecular Formula	C5H10O4
Molecular Weight	134.13 g/mol
Synonyms	(S)-Methyl 2,4-Dihydroxybutyrate; (S)-Methyl 2,4-Dihydroxybutanoic Acid Methyl Ester; (2S)-Methyl 2,4-Dihydroxybutanoate; L-Methyl 2,4-Dihydroxybutyrate; Methyl (S)-2,4-Dihydroxybutanoate; (S)-2,4-Dihydroxybutyric Acid Methyl Ester; (S)-Methyl 2,4-Dihydroxybutyric Acid Ester
EINECS	Contact for details

Quality Control

Our (S)-Methyl 2,4-Dihydroxybutanoate is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques, including chiral HPLC, to guarantee the specified enantiomeric excess (e.e.). A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.