Description

Cyclopropanecarboxylic Acid, 1-Ethynyl-2-Methyl-, Methyl Ester, cis- (9Ci) is a specialized organic compound featuring a cyclopropane ring and an ethynyl group, making it a valuable chiral building block in advanced synthetic chemistry. Its unique cis-configured, strained-ring structure is critical for constructing complex molecular architectures with high stereochemical precision. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, particularly for applications requiring specific three-dimensional spatial arrangements.

Application

This high-value chemical intermediate serves as a key precursor in several advanced research and development fields:

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands in asymmetric catalysis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal or mechanical properties derived from the strained ring system.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme function and biological pathways due to its alkyne "click chemistry" handle.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Ethynyl-2-Methyl-, Methyl Ester, cis- (9Ci)
CAS No.	153943-62-5
Molecular Formula	C8H10O2
Molecular Weight	138.16 g/mol
Synonyms	Methyl cis-1-Ethynyl-2-methylcyclopropanecarboxylate; cis-1-Ethynyl-2-methylcyclopropanecarboxylic acid methyl ester; (1R,2S)-1-Ethynyl-2-methylcyclopropanecarboxylic Acid Methyl Ester; (1S,2R)-1-Ethynyl-2-methylcyclopropanecarboxylic Acid Methyl Ester; Methyl (1R,2S)-1-ethynyl-2-methylcyclopropanecarboxylate; 1-Ethynyl-2-methylcyclopropanecarboxylic acid methyl ester, cis-; Cyclopropanecarboxylic acid, 1-ethynyl-2-methyl-, methyl ester, (1R,2S)-rel-
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 1-Ethynyl-2-Methyl-, Methyl Ester, cis- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, and NMR to confirm identity, isomeric purity (cis- configuration), and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. For long-term storage, consider under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Isomeric Purity (cis-)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.