Description

Cyclopropanecarboxylic Acid, 1-Ethynyl-2-Methyl-, Methyl Ester, trans- (9Ci) is a specialized cyclopropane derivative featuring both an ethynyl and an ester functional group, making it a valuable chiral building block in advanced organic synthesis. Its unique trans-configuration and reactive alkyne moiety are critical for constructing complex molecular architectures with high stereochemical fidelity. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for constructing constrained ring systems.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the cyclopropane ring enhances biological activity and stability.
• Material Science Research: Acts as a monomer or precursor for developing specialized polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags due to the reactivity of the alkyne group for click chemistry applications.
• Catalyst & Ligand Development: Employed as a precursor for synthesizing novel chiral ligands and organometallic catalysts for asymmetric synthesis.
• Academic & Industrial R&D: A fundamental tool for methodological development and exploring new chemical spaces in synthetic organic chemistry laboratories.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Ethynyl-2-Methyl-, Methyl Ester, trans- (9Ci)
CAS No.	153943-61-4
Molecular Formula	C8H10O2
Molecular Weight	138.16 g/mol
Synonyms	trans-1-Ethynyl-2-methylcyclopropanecarboxylic acid methyl ester; Methyl trans-1-ethynyl-2-methylcyclopropanecarboxylate; (1R,2S)-1-Ethynyl-2-methylcyclopropanecarboxylic acid methyl ester; (1S,2R)-1-Ethynyl-2-methylcyclopropanecarboxylic acid methyl ester; 1-Ethynyl-2-methylcyclopropanecarboxylic Acid Methyl Ester; trans-Methyl 1-ethynyl-2-methylcyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Ethynyl-2-Methyl-, Methyl Ester, trans- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including chiral purity verification, to support your critical synthesis work. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.