Description

n-(Phenoxycarbonyl)-L-Valine Methyl Ester is a specialized chiral building block and protected amino acid derivative. This compound is critical for the controlled synthesis of peptides and peptidomimetics, offering precise stereochemistry and functional group protection. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a protected valine derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Bioconjugation Chemistry: Used in the preparation of labeled peptides or protein conjugates for diagnostic and research applications.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the creation of combinatorial libraries.
• Chemical Biology Probes: A precursor for synthesizing enzyme inhibitors or molecular probes to study biological pathways.

Basic Information

Product Name	n-(Phenoxycarbonyl)-L-Valine Methyl Ester
CAS No.	153441-77-1
Molecular Formula	C14H19NO5
Molecular Weight	281.30 g/mol
Synonyms	L-Valine, N-[(phenoxycarbonyl)]-, methyl ester; Methyl N-(phenoxycarbonyl)-L-valinate; Methyl (2S)-3-methyl-2-[(phenoxycarbonyl)amino]butanoate; N-Carboxy-L-valine Methyl Ester Phenyl Ester; N-Phenoxycarbonyl-L-valine Methyl Ester; Z-L-Val-OMe (common abbreviation); N-(Phenoxycarbonyl)valine Methyl Ester
EINECS	Contact for details

Quality Control

Our n-(Phenoxycarbonyl)-L-Valine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.