Description

Butanoic Acid, 2-Cyano-3-Fluoro-2-Hydroxy-3-Methyl-, Ethyl Ester (9Ci) is a specialized fluorinated cyano ester building block with significant synthetic utility. This high-value intermediate is crucial for introducing both fluorine and cyano functional groups into target molecules, enabling the development of compounds with enhanced biological activity and modified physical properties. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated and cyano-substituted heterocycles and complex molecules in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides where the fluorine atom improves metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for specialty monomers or additives aimed at creating polymers with specific optical or surface properties.
• Liquid Crystal & OLED Materials: Potential building block for fluorine-containing components in electronic display and lighting technologies.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated probes and tags for studying biological mechanisms and diagnostics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for client-specific synthesis projects requiring this precise molecular architecture.

Basic Information

Product Name	Butanoic Acid, 2-Cyano-3-Fluoro-2-Hydroxy-3-Methyl-, Ethyl Ester (9Ci)
CAS No.	153431-42-6
Molecular Formula	C9H12FNO3
Molecular Weight	201.20 g/mol
Synonyms	Ethyl 2-Cyano-3-fluoro-2-hydroxy-3-methylbutanoate; 2-Cyano-3-fluoro-2-hydroxy-3-methylbutyric Acid Ethyl Ester; 3-Fluoro-2-hydroxy-2-cyano-3-methylbutyric Acid Ethyl Ester; Butanoic acid, 2-cyano-3-fluoro-2-hydroxy-3-methyl-, ethyl ester; 153431-42-6; Ethyl 3-fluoro-2-hydroxy-2-cyano-3-methylbutyrate
EINECS	Contact for details

Quality Control

Every batch of Butanoic Acid, 2-Cyano-3-Fluoro-2-Hydroxy-3-Methyl-, Ethyl Ester is produced and analyzed under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates, ensuring traceability and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions. Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.