Description

7-(7-((1,1'-Biphenyl-4-Yl)Methyl)-2-(4-Fluorophenyl)-4,5,6,7-Tetrahydro-2H-Indazol-3-Yl)-3,5-Dihydroxy-6-Heptenoic Acid CAS NO 153321-50-7 is a high-purity, synthetic organic compound belonging to the class of complex heterocyclic carboxylic acids. This compound is of significant interest for its role as a key pharmaceutical intermediate in advanced research and development. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, particularly in oncology and metabolic disease research.
• Biochemical Research: Used as a reference standard or a precursor in studies involving enzyme inhibition and receptor binding assays.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of new chemical entities (NCEs).
• Process Chemistry: Employed in route scouting and optimization for scalable GMP manufacturing processes.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and synthetic methodology projects.

Basic Information

Product Name	7-(7-((1,1'-Biphenyl-4-Yl)Methyl)-2-(4-Fluorophenyl)-4,5,6,7-Tetrahydro-2H-Indazol-3-Yl)-3,5-Dihydroxy-6-Heptenoic Acid
CAS No.	153321-50-7
Molecular Formula	C34H31FN2O4
Molecular Weight	550.62 g/mol
Synonyms	7-[7-[(1,1'-Biphenyl-4-yl)methyl]-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-6-heptenoic acid; 153321-50-7; Biphenyl-indazole heptenoic acid derivative; (E)-7-(7-(([1,1'-Biphenyl]-4-yl)methyl)-2-(4-fluorophenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl)-3,5-dihydroxyhept-6-enoic acid
EINECS	Contact for details

Quality Control

Our 7-(7-((1,1'-Biphenyl-4-Yl)Methyl)-2-(4-Fluorophenyl)-4,5,6,7-Tetrahydro-2H-Indazol-3-Yl)-3,5-Dihydroxy-6-Heptenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development from research to commercial scale with cGMP-compliant processes as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.