Description

4-Amidinocyclohexanecarboxylic Acid 4-tert-Butylphenyl Ester is a high-purity, non-peptidic small molecule compound featuring a cyclohexane carboxylic acid scaffold with amidine and tert-butylphenyl ester functional groups. This specific chemical structure makes it a valuable intermediate for the development of pharmaceutical agents and biochemical research tools, particularly as a potential inhibitor for serine proteases like trypsin and related enzymes. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting serine proteases.
• Biochemical Research: Used as a reference standard or inhibitor in enzymatic studies and assay development.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Protease Inhibitor Development: Investigated for potential applications in conditions where trypsin-like enzyme activity is dysregulated.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a protected or functionalized cyclohexane derivative.

Basic Information

Product Name	4-Amidinocyclohexanecarboxylic Acid 4-tert-Butylphenyl Ester
CAS No.	153235-96-2
Molecular Formula	C18H26N2O2
Molecular Weight	302.41 g/mol
Synonyms	4-(Aminocarbonyl)cyclohexanecarboxylic Acid 4-tert-Butylphenyl Ester; 4-Carbamimidoylcyclohexane-1-carboxylic Acid 4-(tert-Butyl)phenyl Ester; 4-tert-Butylphenyl 4-Amidinocyclohexanecarboxylate; 4-(tert-Butyl)phenyl 4-Carbamimidoylcyclohexane-1-carboxylate; BOCA Ester; Trypsin Inhibitor Intermediate; 153235-96-2
EINECS	Contact for details

Quality Control

Our 4-Amidinocyclohexanecarboxylic Acid 4-tert-Butylphenyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.