Description

2-Chloro-4-Iodopyridine-3-Carboxaldehyde is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex heterocyclic scaffolds and functionalized molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific halogenated pyridine motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functional organic materials and liquid crystals due to its electron-deficient aromatic core.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for sequential Suzuki, Stille, and Sonogashira cross-coupling reactions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	2-Chloro-4-Iodopyridine-3-Carboxaldehyde
CAS No.	153034-90-3
Molecular Formula	C6H3ClINO
Molecular Weight	267.45 g/mol
Synonyms	3-Formyl-2-chloro-4-iodopyridine; 2-Chloro-4-iodo-3-pyridinecarboxaldehyde; 2-Chloro-4-iodopyridine-3-carbaldehyde; 4-Iodo-2-chloropyridine-3-carboxaldehyde; 3-Pyridinecarboxaldehyde, 2-chloro-4-iodo-; 153034-90-3; 2-Chloro-4-iodo-3-formylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Iodopyridine-3-Carboxaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.