Description

2-Chloro-4-Iodo-3-Methylpyridine is a halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and valuable building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized heterocyclic compounds for advanced materials, such as organic semiconductors or liquid crystals.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for selective palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	2-Chloro-4-Iodo-3-Methylpyridine
CAS No.	153034-88-9
Molecular Formula	C6H5ClIN
Molecular Weight	253.47 g/mol
Synonyms	3-Methyl-2-chloro-4-iodopyridine; 4-Iodo-2-chloro-3-methylpyridine; 2-Chloro-4-iodo-3-picoline; Pyridine, 2-chloro-4-iodo-3-methyl-; 153034-88-9
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Iodo-3-Methylpyridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.