Description

2-Butenoic Acid, 3-[(Ethoxycarbonyl)Amino]-, Methyl Ester is a specialized α,β-unsaturated ester derivative with a carbamate-protected amino group, serving as a versatile building block in organic synthesis. This compound is valued for its dual reactive sites, enabling its use in the construction of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical intermediate, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing β-amino acid or heterocyclic motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require specific carbamate or unsaturated ester functionalities.
• Peptidomimetics & Bioactive Molecules: Serves as a constrained scaffold for designing peptide analogs and other bioactive compounds with improved metabolic stability.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Chemical Synthesis Reagent: Employed in Michael addition reactions, cyclizations, and as a precursor for further functional group transformations in complex organic synthesis.

Basic Information

Product Name	2-Butenoic Acid, 3-[(Ethoxycarbonyl)Amino]-, Methyl Ester
CAS No.	152900-47-5
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	Methyl 3-[(ethoxycarbonyl)amino]but-2-enoate; 3-(Ethoxycarbonylamino)-2-butenoic Acid Methyl Ester; Methyl 3-(N-ethoxycarbonylamino)crotonate; 3-Carbethoxyamino-2-butenoic Acid Methyl Ester; (E)-Methyl 3-((ethoxycarbonyl)amino)but-2-enoate; But-2-enoic acid, 3-[(ethoxycarbonyl)amino]-, methyl ester; A potential intermediate for Cefcapene Pivoxil.
EINECS	Contact for details

Quality Control

Our 2-Butenoic Acid, 3-[(Ethoxycarbonyl)Amino]-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.