Description

5-Bromo-2-Methoxy-3-Nitro-Pyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by research chemists and process development scientists for the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging its pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Utilized to create tagged molecules or inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromo-2-Methoxy-3-Nitro-Pyridine
CAS No.	152684-30-5
Molecular Formula	C6H5BrN2O3
Molecular Weight	233.02 g/mol
Synonyms	3-Nitro-5-bromo-2-methoxypyridine; 2-Methoxy-3-nitro-5-bromopyridine; 5-Bromo-2-methoxy-3-nitropyridine; Pyridine, 5-bromo-2-methoxy-3-nitro-; 152684-30-5; 5-Br-2-MeO-3-NO2-Pyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Methoxy-3-Nitro-Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.