Description

D-Mannonic Acid, 2,6-Anhydro-, γ-Lactone (9Ci) is a specialized carbohydrate derivative and chiral building block of significant interest in advanced organic synthesis. Its unique anhydro-lactone structure makes it a valuable precursor for synthesizing complex molecules, particularly in the pharmaceutical and fine chemical industries. This high-purity intermediate is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), nucleoside analogs, and other biologically active compounds where stereochemical control is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of nucleoside-based drugs, antiviral agents, and other complex therapeutic molecules.
• Fine Chemical Synthesis: Used as a building block in the production of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
• Biochemical Research: Serves as a standard or precursor in carbohydrate chemistry research and enzymatic studies.
• Glycochemistry: Employed in the synthesis of complex carbohydrates, glycoconjugates, and glycomimetics for diagnostic and therapeutic applications.
• Cosmetic Ingredient Synthesis: Potential intermediate for producing specialty esters or derivatives used in high-end cosmetic formulations.

Basic Information

Product Name	D-Mannonic Acid, 2,6-Anhydro-, γ-Lactone (9Ci)
CAS No.	152492-78-9
Molecular Formula	C6H8O6
Molecular Weight	176.12 g/mol
Synonyms	2,6-Anhydro-D-mannonic acid γ-lactone; D-Mannono-1,4-lactone, 2,6-anhydro-; 2,6-Anhydro-D-gulono-1,4-lactone; (3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one; D-Mannonic acid γ-lactone, 2,6-anhydro-; 1,4-Anhydro-2,6-dideoxy-D-mannono-1,4-lactone (related structure); Carbohydrate lactone derivative CAS 152492-78-9
EINECS	Contact for details

Quality Control

Every batch of D-Mannonic Acid, 2,6-Anhydro-, γ-Lactone is produced and tested under a strict quality management system to ensure consistency and high purity suitable for research and synthesis applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable supply for critical development and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.