Description

5-Chlorothieno[3,2-B]Pyridine-3-Carbaldehyde is a high-value, multi-functional heterocyclic building block and key synthetic intermediate. Its unique fused-ring structure, combining thiophene and pyridine motifs with an aldehyde functional group, makes it indispensable for advanced organic synthesis and pharmaceutical research. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Serves as a key building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science & OLED Development: Used in the synthesis of organic semiconductors, electron-transport materials, and luminescent compounds for electronic and optoelectronic devices.
• Ligand Synthesis for Catalysis: The aldehyde group allows for the construction of complex chelating ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for exploring new chemical spaces in discovery research.

Basic Information

Product Name	5-Chlorothieno[3,2-B]Pyridine-3-Carbaldehyde
CAS No.	152420-81-0
Molecular Formula	C8H4ClNOS
Molecular Weight	197.64 g/mol
Synonyms	5-Chlorothieno[3,2-b]pyridine-3-carboxaldehyde; 3-Formyl-5-chlorothieno[3,2-b]pyridine; 5-Chloro-3-formylthieno[3,2-b]pyridine; 152420-81-0; Thieno[3,2-b]pyridine-3-carbaldehyde, 5-chloro-; 5-Chloro-thieno[3,2-b]pyridine-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Chlorothieno[3,2-B]Pyridine-3-Carbaldehyde is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC-MS for impurity profiling, to ensure consistency and reliability for your critical research and development projects. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.