Description

Cyclopropanecarboxylic Acid, 2-Fluoro-, 1,1-Dimethylethyl Ester, trans- (9Ci) CAS NO 152237-15-5 is a high-purity, fluorinated cyclopropane derivative serving as a critical chiral building block in advanced organic synthesis. This compound is valued for its unique structural motif, which imparts desirable conformational and metabolic properties to target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides, where the fluorinated cyclopropane ring can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique physical properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes to study enzyme mechanisms and biological pathways due to its fluorine label and rigid structure.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Fluoro-, 1,1-Dimethylethyl Ester, trans- (9Ci)
CAS No.	152237-15-5
Molecular Formula	C9H15FO2
Molecular Weight	174.21 g/mol
Synonyms	trans-2-Fluorocyclopropanecarboxylic acid tert-butyl ester; tert-Butyl trans-2-fluorocyclopropanecarboxylate; 1,1-Dimethylethyl trans-2-fluorocyclopropanecarboxylate; trans-2-Fluoro-1-cyclopropanecarboxylic acid tert-butyl ester; (1R,2S)-rel-2-Fluorocyclopropanecarboxylic acid 1,1-dimethylethyl ester; (1S,2R)-rel-2-Fluorocyclopropanecarboxylic acid 1,1-dimethylethyl ester; 2-Fluorocyclopropanecarboxylic acid tert-butyl ester, trans-
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Fluoro-, 1,1-Dimethylethyl Ester, trans- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.