Description

Agelasphin 11 is a potent, naturally derived α-galactosylceramide, a class of compounds known for their significant immunomodulatory properties. This high-purity compound is critical for advanced research and development in immunology and oncology. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies investigating novel therapeutic pathways, particularly in the activation of invariant natural killer T (iNKT) cells.

Application

• Immunology Research: As a reference standard and active agent in studies of iNKT cell activation, cytokine production, and immune response modulation.
• Preclinical Drug Development: Serving as a lead compound or pharmacodynamic marker in the development of novel immunotherapies and vaccine adjuvants.
• Oncology Research: Investigation of anti-tumor activity and potential use in cancer immunotherapy protocols.
• Infectious Disease Studies: Research into host defense mechanisms and immune potentiation against various pathogens.
• Biochemical Assay Development: Use as a critical reagent in high-throughput screening and binding assays targeting CD1d receptors.
• Academic & Institutional Research: Fundamental research into glycolipid biology, antigen presentation, and cellular signaling pathways.

Basic Information

Product Name	Agelasphin 11
CAS No.	152139-44-1
Molecular Formula	C46H89NO9
Molecular Weight	800.21 g/mol
Synonyms	KRN7000; (2S,3S,4R)-1-O-(α-D-Galactopyranosyl)-2-(N-hexacosanoylamino)-1,3,4-octadecanetriol; α-Galactosylceramide; α-GalCer; Agelasphin-11; AGSP-11; Synthetic Agelasphin; Immunostimulatory Glycolipid; CD1d Ligand
EINECS	Contact for details

Quality Control

Every batch of Agelasphin 11 is manufactured and tested under strict quality management systems to ensure identity, purity, and consistency suitable for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.