Description

5-(tert-Butyldimethylsilyl)-1-Methyl-1H& CAS NO 152120-66-6 is a specialized organosilicon compound featuring a tert-butyldimethylsilyl (TBDMS) protecting group. This compound is a critical intermediate in advanced organic synthesis, particularly valued for its role in protecting sensitive functional groups during complex multi-step reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for nucleoside and heterocyclic compounds.
• Nucleoside Protection: Used to protect hydroxyl groups on nucleosides and nucleotides during oligonucleotide and prodrug synthesis.
• Fine Chemical Synthesis: Serves as a versatile protecting group reagent in multi-step organic synthesis for complex natural products and specialty chemicals.
• Agrochemical Research: Employed in the research and development of new pesticides and herbicides where selective protection is required.
• Material Science Precursor: Acts as a precursor in the development of silicon-containing polymers and advanced materials.

Basic Information

Product Name	5-(tert-Butyldimethylsilyl)-1-Methyl-1H& CAS NO 152120-66-6
CAS No.	152120-66-6
Molecular Formula	C₁₂H₂₆N₂Si
Molecular Weight	226.44 g/mol
Synonyms	1-Methyl-5-[(1,1-dimethylethyl)dimethylsilyl]-1H-pyrazole; 1-Methyl-5-(tert-butyldimethylsilyl)pyrazole; 5-(Tert-Butyldimethylsilyl)-1-methyl-1H-pyrazole; 5-(tert-Butyldimethylsilyl)-1-methylpyrazole; TBDMS-1-methylpyrazole
EINECS	Contact for details

Quality Control

Our 5-(tert-Butyldimethylsilyl)-1-Methyl-1H& CAS NO 152120-66-6 is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. All products undergo rigorous analytical testing, including HPLC, NMR, and GC analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.