Description

Carbamic Acid, 5-Hexynyl-, 1,1-Dimethylethyl Ester (9Ci) is a specialized alkyne-functionalized carbamate derivative, serving as a versatile building block in advanced organic synthesis. Its core value lies in the protected amine and terminal alkyne functionalities, which enable efficient coupling reactions and modular molecular construction under mild conditions. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and materials science who require reliable, structurally precise components for creating novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in creating molecules with alkyne handles for click chemistry applications.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that require specific carbamate or alkyne motifs.
• Peptide & Protein Conjugation: The terminal alkyne group facilitates site-specific bioconjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for labeling and modifying biomolecules.
• Polymer & Materials Science: Serves as a monomer or cross-linking agent in the synthesis of functional polymers, dendrimers, and smart materials.
• Chemical Probe Development: Integral for creating molecular probes and diagnostic agents used in biochemical and cellular imaging studies.
• Organic Synthesis Scaffold: Provides a protected amine precursor for further functionalization, enabling complex multi-step synthetic routes in medicinal chemistry.

Basic Information

Product Name	Carbamic Acid, 5-Hexynyl-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	151978-58-4
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	tert-Butyl (5-hexynyl)carbamate; N-(5-Hexynyl)carbamic Acid 1,1-Dimethylethyl Ester; BOC-5-Hexynylamine; 5-Hexyn-1-amine, N-BOC-protected; N-(tert-Butoxycarbonyl)-5-hexyn-1-amine; 6-(tert-Butoxycarbonylamino)hex-1-yne; (5-Hexynyl)carbamic Acid tert-Butyl Ester; BOC-NH-(CH2)4-C≡CH
EINECS	Contact for details

Quality Control

Our Carbamic Acid, 5-Hexynyl-, 1,1-Dimethylethyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.