Description

Carbamic Acid, 4-Pentynyl-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic building block featuring a terminal alkyne functional group protected by a tert-butyloxycarbonyl (Boc) moiety. This compound is of significant value in synthetic organic chemistry, particularly for the construction of complex molecules via click chemistry and other coupling reactions. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, especially those requiring alkyne-azide cycloaddition (CuAAC) for bioconjugation or probe attachment.
• Agrochemical Research: Used in the design and development of new pesticides and herbicides, where the alkyne group enables modular structure-activity relationship (SAR) studies.
• Peptide & Protein Modification: The Boc-protected amine allows for selective deprotection and further functionalization, making it useful in peptide synthesis and for labeling biomolecules.
• Material Science: Acts as a monomer or cross-linker in the production of specialty polymers, dendrimers, and functional surfaces with tailored properties.
• Chemical Biology Probes: Employed in the creation of activity-based probes and diagnostic agents for studying biological pathways and disease mechanisms.
• Ligand & Catalyst Development: Provides a versatile handle for constructing sophisticated ligand frameworks used in homogeneous catalysis.

Basic Information

Product Name	Carbamic Acid, 4-Pentynyl-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	151978-50-6
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	tert-Butyl (4-pentynyl)carbamate; N-(4-Pentynyl)carbamic Acid tert-Butyl Ester; 4-Pentyn-1-amine, N-Boc-protected; Boc-4-pentynylamine; N-Boc-4-pentyn-1-amine; 1-Boc-amino-4-pentyne; (4-Pentynyl)carbamic Acid 1,1-Dimethylethyl Ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, 4-Pentynyl-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as indicated on the label. This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.