Description

3',6'-Dihydroxy-3-Oxospiro-(Isobenzofuran-1(3H),9'-9H-Xanthene)-6-Carboxylic Acid 2-(Mercaptoacetyl)Hydrazide is a high-purity, specialized organic compound designed for advanced research and development applications. Its unique spiro-xanthene structure, functionalized with carboxylic acid and mercaptoacetyl hydrazide groups, makes it a valuable intermediate for synthesizing novel fluorescent probes and bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors seeking to develop new diagnostic agents or functional materials.

Application

• Fluorescent Probe Synthesis: A key precursor for developing sensitive and selective fluorescent sensors and labeling reagents for biological imaging and diagnostic assays.
• Pharmaceutical Intermediate: Used in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting specific biological pathways.
• Bioconjugation Chemistry: The carboxylic acid and hydrazide functionalities enable covalent attachment to proteins, antibodies, or nanoparticles for creating targeted diagnostic or therapeutic conjugates.
• Materials Science Research: Serves as a building block for developing novel organic electronic materials or photoresponsive polymers due to its xanthene core.
• Chemical Biology Tools: Utilized in creating activity-based probes for studying enzyme function or cellular processes.
• Analytical Reagent Development: Acts as a derivatization agent or a core structure for chelating agents in analytical chemistry methodologies.

Basic Information

Product Name	3',6'-Dihydroxy-3-Oxospiro-(Isobenzofuran-1(3H),9'-9H-Xanthene)-6-Carboxylic Acid 2-(Mercaptoacetyl)Hydrazide
CAS No.	151890-76-5
Molecular Formula	C24H16N2O8S
Molecular Weight	492.46 g/mol
Synonyms	Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diol, 6-carboxylic acid, 2-[(2-mercaptoacetyl)hydrazide]; 6-Carboxyfluorescein mercaptoacetyl hydrazide; 6-FAM mercaptoacetyl hydrazide; Mercaptoacetyl hydrazide of 6-carboxyfluorescein; 6-FAM-MAH; Fluorescein-based thiol-reactive probe precursor; 151890-76-5; 6-Carboxyfluorescein-2-(mercaptoacetyl)hydrazide
EINECS	Contact for details

Quality Control

Every batch of 3',6'-Dihydroxy-3-Oxospiro-(Isobenzofuran-1(3H),9'-9H-Xanthene)-6-Carboxylic Acid 2-(Mercaptoacetyl)Hydrazide is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider handling and storing under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.