Description

3-Cyclobutene-1,2-Dicarboxylicacid,Monomethylester,(1R,2S)-(9Ci) is a high-purity chiral synthon and a key intermediate in advanced organic synthesis. This compound matters for its role in constructing complex, stereochemically defined molecular architectures, which are critical for developing active pharmaceutical ingredients (APIs) and specialty materials. It is primarily needed by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and material science, where precise stereochemistry is paramount for product efficacy and performance.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel, stereochemically pure drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with specific chiral activity.
• Material Science Research: Serves as a precursor for developing specialized polymers and liquid crystals with tailored optical or mechanical properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral scaffold in the development of asymmetric catalytic systems.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.
• Fine Chemical Production: Integral to the multi-step synthesis of complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	3-Cyclobutene-1,2-Dicarboxylicacid,Monomethylester,(1R,2S)-(9Ci)
CAS No.	151715-95-6
Molecular Formula	C7H8O4
Molecular Weight	156.14 g/mol
Synonyms	(1R,2S)-3-Cyclobutene-1,2-dicarboxylic acid monomethyl ester; (1R,2S)-Methyl 3-cyclobutene-1,2-dicarboxylate; (1R,2S)-1,2-Cyclobutenedicarboxylic acid monomethyl ester; (1R,2S)-CBDA monomethyl ester; (1R,2S)-Cyclobut-3-ene-1,2-dicarboxylic acid methyl ester; (1R,2S)-Dimethyl cyclobut-3-ene-1,2-dicarboxylate isomer; Monomethyl (1R,2S)-3-cyclobutene-1,2-dicarboxylate
EINECS	Contact for details

Quality Control

Our 3-Cyclobutene-1,2-Dicarboxylicacid,Monomethylester,(1R,2S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.