Description

2-Oxabicyclo[2.2.2]Oct-5-En-3-One, 8-Acetyl-, (1Alpha,4Alpha,8R*)- (9Ci) is a high-purity, specialized bicyclic lactone derivative with a defined stereochemistry, serving as a critical chiral building block and synthetic intermediate. Its unique fused ring structure and acetyl functional group make it valuable for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for applications in asymmetric synthesis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in asymmetric synthesis.
• Organic Synthesis Building Block: Used in complex multi-step organic reactions to construct intricate bicyclic or polycyclic frameworks found in natural products and specialty chemicals.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of specialized chiral ligands or organocatalysts used in enantioselective transformations.
• Academic and R&D Research: Employed in university and industrial research laboratories for methodological studies in synthetic organic chemistry and stereochemistry.
• Fine Chemical Production: Utilized in the small-scale, high-value production of specialty fine chemicals and advanced materials requiring specific stereochemical purity.
• Agrochemical Research: Potential intermediate in the development of new chiral agrochemicals, such as herbicides or pesticides, where stereochemistry affects bioactivity.

Basic Information

Item	Detail
Product Name	2-Oxabicyclo[2.2.2]Oct-5-En-3-One, 8-Acetyl-, (1Alpha,4Alpha,8R*)- (9Ci)
CAS No.	151699-35-3
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	8-Acetyl-2-oxabicyclo[2.2.2]oct-5-en-3-one; (1α,4α,8R*)-8-Acetyl-2-oxabicyclo[2.2.2]oct-5-en-3-one; 8-Acetyl-2-oxabicyclo[2.2.2]oct-5-en-3-one, (1alpha,4alpha,8R*)-; Bicyclic acetyl lactone; 2-Oxabicyclo[2.2.2]oct-5-ene-3-one, 8-acetyl-, (1α,4α,8R*)-; 151699-35-3; (1R,4R,8R)-8-Acetyl-2-oxabicyclo[2.2.2]oct-5-en-3-one (relative configuration)
EINECS	Contact for details

Quality Control

Every batch of 2-Oxabicyclo[2.2.2]Oct-5-En-3-One, 8-Acetyl-, (1Alpha,4Alpha,8R*)- (9Ci) is produced and analyzed under strict quality management protocols to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Our products undergo rigorous quality testing, including chromatographic and spectroscopic methods, to ensure compliance with customer specifications and industry best practices. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Residue on Ignition	< 0.1%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.