Description

4-Hydroxy-4-(3-Nitro-Phenyl)-2-Oxo-But-3-Enoic Acid Methyl Ester is a specialized organic intermediate characterized by its nitro-phenyl and β-keto ester functional groups. This compound matters for its role as a versatile building block in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced material precursors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those containing nitro-aromatic or β-keto ester motifs.
• Agrochemical Synthesis: Used in research and development for creating novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a versatile building block for synthesizing dyes, pigments, and other performance chemicals.
• Academic & Industrial Research: Employed in organic chemistry research for studying reaction mechanisms, such as Michael additions and cyclization reactions, due to its reactive carbonyl and alkene groups.
• Material Science: Investigated as a monomer or cross-linking agent in the development of specialized polymers and advanced materials.

Basic Information

Product Name	4-Hydroxy-4-(3-Nitro-Phenyl)-2-Oxo-But-3-Enoic Acid Methyl Ester
CAS No.	151646-59-2
Molecular Formula	C11H9NO6
Molecular Weight	251.19 g/mol
Synonyms	Methyl 4-hydroxy-4-(3-nitrophenyl)-2-oxobut-3-enoate; 4-Hydroxy-4-(3-nitrophenyl)-2-oxobut-3-enoic acid methyl ester; 3-Butenoic acid, 4-hydroxy-4-(3-nitrophenyl)-2-oxo-, methyl ester; (3-Nitrophenyl)(oxo)acetic acid methyl ester enol; β-Keto ester derivative of 3-nitrobenzaldehyde
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-4-(3-Nitro-Phenyl)-2-Oxo-But-3-Enoic Acid Methyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, impurities, and physical characteristics are available for every shipment. We are committed to meeting the stringent requirements of research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.