Description

Zinquin Ethyl Ester is a highly specific, cell-permeable fluorescent probe designed for the selective detection of labile zinc (Zn²⁺) ions in biological systems. This compound matters because it provides researchers with a critical tool for visualizing and quantifying intracellular zinc pools, which are essential for understanding its role in neurotransmission, immune function, and cellular signaling. Life science researchers, pharmaceutical developers, and diagnostic manufacturers need this high-purity reagent for applications in neuroscience, immunology, and molecular biology research.

Application

• Intracellular Zinc Imaging: Fluorescent detection and visualization of labile Zn²⁺ in live cells and tissues using fluorescence microscopy.
• Neuroscience Research: Studying the role of synaptic zinc in neuronal communication, particularly in glutamatergic pathways and conditions like epilepsy or neurodegeneration.
• Immunological Studies: Probing zinc flux as a signaling mechanism in immune cell activation and function.
• Apoptosis & Cell Biology: Monitoring changes in intracellular zinc levels during programmed cell death and other cellular processes.
• Diagnostic Assay Development: Serving as a key component in the development of fluorescent-based assays for zinc status or related metabolic pathways.
• Pharmaceutical Screening: Used in high-throughput screening platforms to identify compounds that modulate zinc homeostasis.

Basic Information

Product Name	Zinquin Ethyl Ester
CAS No.	151606-29-0
Molecular Formula	C₂₀H₁₈N₂O₃
Molecular Weight	334.37 g/mol
Synonyms	Zinquin ethyl ester; [Ethyl 2-methyl-8-(4-toluenesulfonamido)-6-quinolyloxy]acetate; TSQ derivative; Zinc indicator Zinquin E; Zinc fluorescent probe; N-(6-Methoxy-8-quinolyl)-p-toluenesulfonamide ethyl ester derivative; Labile zinc probe
EINECS	Contact for details

Quality Control

Our Zinquin Ethyl Ester is produced and tested to meet the exacting standards required for sensitive life science research. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure consistent performance and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term storage, consider desiccant or under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Fluorescence Performance	Ex/Em ~368/490 nm in presence of Zn²⁺; Conforms to reference

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.