Description

2-(2-Bromoethoxy)Ethoxy-tert-Butyl-Dimethylsilane is a specialized organosilicon reagent featuring a bromoethoxy linker and a tert-butyldimethylsilyl (TBDMS) protecting group. This compound is valued for its dual functionality, serving as a versatile building block in organic synthesis and a key intermediate for modifying molecular structures. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules and functionalized polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for introducing polyethylene glycol (PEG)-like spacers or for subsequent functional group transformations.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require specific ether and silyl ether functionalities.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for creating specialty silicones, surface-modifying agents, and polymers with tailored properties.
• Protecting Group Chemistry: The TBDMS group is employed to protect hydroxyl groups during complex synthetic sequences, with the bromoethoxy handle allowing for further conjugation or cleavage.
• Bioconjugation & Linker Chemistry: Utilized in the design of cleavable linkers for drug delivery systems, such as antibody-drug conjugates (ADCs), and for bioconjugation strategies.
• Liquid Crystal & OLED Material Research: Acts as a precursor for synthesizing functionalized organic molecules used in electronic displays and organic light-emitting diodes.

Basic Information

Product Name	2-(2-Bromoethoxy)Ethoxy-tert-Butyl-Dimethylsilane
CAS No.	151556-43-3
Molecular Formula	C10H23BrO2Si
Molecular Weight	283.28 g/mol
Synonyms	1-((2-Bromoethoxy)ethoxy)-2,2-dimethylpropyl]dimethylsilane; tert-Butyl[2-(2-bromoethoxy)ethoxy]dimethylsilane; 2-(2-Bromoethoxy)ethoxy-tert-butyldimethylsilane; TBDMS ether of 2-(2-bromoethoxy)ethanol; (2-(2-Bromoethoxy)ethoxy)(tert-butyl)dimethylsilane; Silane, [2-(2-bromoethoxy)ethoxy](1,1-dimethylethyl)dimethyl-; Bromo-PEG2-TBDMS
EINECS	Contact for details

Quality Control

Our 2-(2-Bromoethoxy)Ethoxy-tert-Butyl-Dimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.