Description

4-Pentenoic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, 1,1-Dimethylethyl Ester, (2S)- is a high-purity, chiral protected amino acid derivative of significant value in advanced organic synthesis. This compound matters as a critical building block for constructing complex peptide mimetics and active pharmaceutical ingredients (APIs), offering precise stereochemical control. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, including protease inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates and Active Pharmaceutical Ingredients (APIs).
• Peptidomimetic Research: Used to incorporate non-natural amino acid structures into peptide chains to enhance stability and biological activity.
• Protease Inhibitor Development: Serves as a crucial component in the design and synthesis of inhibitors for various enzymatic targets.
• Chemical Biology Probes: Employed in the creation of labeled or modified peptides for studying protein-protein interactions and cellular pathways.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in stereoselective reactions to construct complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	4-Pentenoic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, 1,1-Dimethylethyl Ester, (2S)-
CAS No.	151436-20-3
Molecular Formula	C15H25NO4
Molecular Weight	283.36 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]-4-pentenoic acid tert-butyl ester; Boc-L-2-Amino-4-pentenoic acid O-t-butyl ester; tert-Butyl (2S)-2-[(tert-butoxycarbonyl)amino]-4-pentenoate; (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)pent-4-enoate; Boc-L-Homoallylglycine-OtBu; Boc-L-homoallylglycine tert-butyl ester; L-2-(Boc-amino)-4-pentenoic acid tert-butyl ester; N-Boc-L-2-amino-4-pentenoic acid t-butyl ester
EINECS	Contact for details

Quality Control

Our production of 4-Pentenoic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, 1,1-Dimethylethyl Ester, (2S)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to comprehensive in-house specifications, which typically include chiral purity, chemical purity, and identity confirmation. Certificates of Analysis (COA) detailing all test results are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.