Description

2-Chloro-5-Nitronicotinic Acid Ethyl Ester is a high-purity, versatile nitropyridine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both chloro and nitro substituents on the pyridine ring, makes it a valuable building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and industrial R&D departments focused on pharmaceutical development, agrochemical synthesis, and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and anti-infective pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive halogen and nitro groups.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers and liquid crystals.
• Chemical Research & Development: A fundamental building block for medicinal chemists exploring structure-activity relationships (SAR) and synthesizing new chemical entities (NCEs).
• Dye and Pigment Intermediate: Utilized in the synthesis of complex organic dyes and pigments due to its nitro-aromatic core.

Basic Information

Product Name	2-Chloro-5-Nitronicotinic Acid Ethyl Ester
CAS No.	151322-83-7
Molecular Formula	C8H7ClN2O4
Molecular Weight	230.61 g/mol
Synonyms	Ethyl 2-Chloro-5-nitronicotinate; 2-Chloro-5-nitro-3-pyridinecarboxylic Acid Ethyl Ester; 3-Pyridinecarboxylic acid, 2-chloro-5-nitro-, ethyl ester; 151322-83-7; Ethyl 2-chloro-5-nitropyridine-3-carboxylate; 2-Chloro-5-nitropyridine-3-carboxylic acid ethyl ester; 5-Nitro-2-chloronicotinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Nitronicotinic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and industrial applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.